Identification of transcriptional regulators of immune evasion across cancers: an alternative immunotherapeutic strategy for cholangiocarcinoma
Current immunotherapies are ineffectively designed toward single-target inhibition in a complex multifactored process. Moreover, available therapeutics are incapable of meeting ...
Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model
This research emphasizes the potential of photothermal therapy (PTT) as an effective cancer treatment using ...
Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells
Cholangiocarcinoma (CCA) is a type of cancer that affects the lining of the bile ducts and is particularly common in ...
SRPK Inhibitors Reduce the Phosphorylation and Translocation of SR Protein Splicing Factors, thereby Correcting BIN1, MCL-1 and BCL2 Splicing Errors and Enabling Apoptosis of Cholangiocarcinoma Cells
Cholangiocarcinoma (CCA), a common bile duct cancer in Thailand, has poor survival rates due to limited diagnostic and treatment options ...
Identification and preclinical evaluation of MMV676558 as a promising therapeutic candidate against Clostridioides difficile
Clostridioides difficile is a bacterium that causes severe diarrhea, especially after antibiotic use. Current treatments, like fidaxomicin and vancomycin, work ...
Quantum dots as a fluorescent labeling tool for live-cell imaging of Leptospira.
In this study, cadmium telluride quantum dots (CdTe QDs) was synthesized and modified surface with concanavalin A (ConA), a carbohydrate-binding ...
Antioxidant and antimicrobial activities of mango peel and radish peel-a comparative investigation
The study explored the antioxidant and antimicrobial properties of ethanolic extracts from Bao Mango and Thai daikon radish peels ...
Anti-cancer Activity of Ethanolic Extract from ‘Bao’ mango (Mangifera indica) Peel and Its Nanoencapsulation Against Triple-Negative Breast Cancer Cell Lines
This work, 'Bao' mango peel extract (MPE) was investigated for its antioxidant and anti-cancer activities. Furthermore, after encapsulation with ...
The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile: evolution and drug resistance perspective
Secondary active transporters move substances across cell membranes in both eukaryotic and prokaryotic organisms, using different ...
Development of Carbon Dots Synthesized from Green Tea and Alpha-Hydroxyl Acids with Enhanced Antioxidant Activity, Photostability and UV Protection Properties
The exhaustion of the ozone layer in the atmosphere has increased UV radiation penetrating the earth’s surface, leading to severe ...