Nanoencapsulation of vitamin B2 using chitosan-modified PLGA nanoparticles: synthesis, characterization, and in vitro studies on simulated gastrointestinal stability and delivery
Vitamin B2 (riboflavin) is important for keeping our cells healthy, but it breaks down easily in light, does not dissolve ...
Determination of 3-hydroxyanthranilic acid in the sweat of healthy older adults.
3-Hydroxyanthranillic acid (3HAA) is a substance made during tryptophan metabolism and is linked to aging and age-related diseases. This study ...
Development and in vitro evaluation of ursolic acid-loaded poly(lactic-co-glycolic acid) nanoparticles in cholangiocarcinoma
Cholangiocarcinoma (CCA) is a type of cancer that affects the bile ducts and is a major health issue in northeastern ...
Mechanisms and applications of bacterial luciferase and its auxiliary enzymes
Bacterial luciferase (LuxAB) catalyzes the conversion of reduced flavin mononucleotide (FMNH2), oxygen, and a long-chain aldehyde ...
KHDRBS3 facilitates self-renewal and temozolomide resistance of glioblastoma cell lines
Glioblastoma is a highly aggressive and fatal tumor characterized by the presence of glioblastoma stem cells (GSCs), which contribute significantly ...
Combinatorial effects of cannabinoid receptor 1 and 2 agonists on characteristics and proteomic alteration in MDA-MB-231 breast cancer cells
The activation of cannabinoid receptor (CB) has been shown to negatively affect breast cancer cell survival. Our previous study also ...
Identification of transcriptional regulators of immune evasion across cancers: an alternative immunotherapeutic strategy for cholangiocarcinoma
Current immunotherapies are ineffectively designed toward single-target inhibition in a complex multifactored process. Moreover, available therapeutics are incapable of meeting ...
Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model
This research emphasizes the potential of photothermal therapy (PTT) as an effective cancer treatment using ...
Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells
Cholangiocarcinoma (CCA) is a type of cancer that affects the lining of the bile ducts and is particularly common in ...
SRPK Inhibitors Reduce the Phosphorylation and Translocation of SR Protein Splicing Factors, thereby Correcting BIN1, MCL-1 and BCL2 Splicing Errors and Enabling Apoptosis of Cholangiocarcinoma Cells
Cholangiocarcinoma (CCA), a common bile duct cancer in Thailand, has poor survival rates due to limited diagnostic and treatment options ...