Transcriptomic Correlation Identifies Cell Model Representatives for MYCN-Amplified Pediatric Neuroblastoma, Downstream Impact of Model Choice on Functional Interpretation, and Potential Drug Repositioning Candidates
Neuroblastoma (NB) is the most common extracranial solid malignancy of children, and MYCN amplification defines a high-risk subtype with poor outcomes ...
Health hazard and risk assessment for occupational health management among three different farmer groups in Phranakorn Si Ayutthaya Province, Thailand
Farmers play an essential role in food production, but agricultural work often exposes them to various occupational hazards that may ...
Enhanced lycopene fortification in eggs using poultry feed containing a carotenoid-oil preparation derived from metabolically engineered baker’s yeast
"In the poultry industry, synthetic dyes are often added to feed to produce the vibrant red-orange yolks that are prefered ...
Red-shifted D-luciferin analogues and their bioluminescence characteristics
D-Luciferin (D-LH2) is the most widely used substrate for beetle luciferases in bioluminescence applications. Here, we ...
Riboflavin-PLGA nanoparticles enhance the effectiveness of the pyruvate carboxylase inhibitor ZY-444 in targeting lipogenesis in colon and breast cancer
New research highlights a powerful way to block aggressive colon and breast cancers by cutting off the energy and fats ...
The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis
Mallotumide A, a natural compound derived from plant roots, has shown high effectiveness in halting the spread and growth of ...
Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration
This research reveals that Erianin, a natural compound found in orchids, can effectively prevent the formation of new fat cells ...
Discovery and biochemical characterization of enzymes completing the 4-hydroxyphenylacetate pathway in Acinetobacter baumannii TH
The 4-hydroxyphenylacetate (4-HPA) degradation pathway enables environmental and pathogenic microbes to assimilate aromatic compounds, yet several steps in Acinetobacter baumannii ...
Structure and reaction mechanisms of a two-component indole monooxygenase from Acinetobacter baumannii
This study investigates how two-component indole monooxygenase from Acinetobacter baumannii converts indole into 3-hydroxyindole. The enzyme system consists of two ...
Enhancing plant growth using anaerobic co-digestate of pig manure, food waste, and coffee grounds
This study demonstrates the use of anaerobic co-digestate liquid (AcoDL) derived from pig manure inoculum, food waste, and spent coffee ...