Integrin α5 mediates intrinsic cisplatin resistance in three-dimensional nasopharyngeal carcinoma spheroids via the inhibition of phosphorylated ERK /caspase-3 induced apoptosis

Tavan Janvilisri

        Nasopharyngeal carcinoma (NPC) originates from the epithelial cells of the nasopharynx. A high incidence is found in China and the Southeast Asia including Thailand. One major contributor to the chemoresistance includes aberrant expression of cell adhesion molecules, such as integrin Read More …

Capturing tumour heterogeneity in pre- and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing

Varodom Charoensawan

    Capturing tumour heterogeneity in pre- and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing   Dr. Charoensawan and his colleagues have employed single-cell RNA-sequencing (scRNA-seq) to explore and characterise ascites-derived cells from a colorectal cancer CRC patient. Analysis Read More …