Riboflavin-PLGA nanoparticles enhance the effectiveness of the pyruvate carboxylase inhibitor ZY-444 in targeting lipogenesis in colon and breast cancer
New research highlights a powerful way to block aggressive colon and breast cancers by cutting off the energy and fats ...
The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis
Mallotumide A, a natural compound derived from plant roots, has shown high effectiveness in halting the spread and growth of ...
Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration
This research reveals that Erianin, a natural compound found in orchids, can effectively prevent the formation of new fat cells ...
Discovery and biochemical characterization of enzymes completing the 4-hydroxyphenylacetate pathway in Acinetobacter baumannii TH
The 4-hydroxyphenylacetate (4-HPA) degradation pathway enables environmental and pathogenic microbes to assimilate aromatic compounds, yet several steps in Acinetobacter baumannii ...
Structure and reaction mechanisms of a two-component indole monooxygenase from Acinetobacter baumannii
This study investigates how two-component indole monooxygenase from Acinetobacter baumannii converts indole into 3-hydroxyindole. The enzyme system consists of two ...
Enhancing plant growth using anaerobic co-digestate of pig manure, food waste, and coffee grounds
This study demonstrates the use of anaerobic co-digestate liquid (AcoDL) derived from pig manure inoculum, food waste, and spent coffee ...
Association of a CD44s-v5-v6 Null Phenotype with Advanced Stage Cholangiocarcinoma: A Preliminary Study
Cholangiocarcinoma is a very aggressive bile duct cancer with poor survival rates, making it crucial for doctors to better predict ...
Kinetic analysis of catalytic activity of G-quadruplex/hemin DNAzyme with flanking adenine nucleotides
This study shows that adding adenine (A) bases to the 3′ end of a G-quadruplex/hemin DNAzyme greatly boosts its enzyme-like ...
Biologics, Biosimilars, and Biobetters: Therapeutic Innovations Reshaping Modern Medicine
Biologic medicines are advanced drugs made from living cells. They are effective for treating cancer and other serious diseases, but ...
Stability of Bioactive Compounds and Wound Healing Activities of Porcine Placental Extract
Porcine placental extract (PPE) is a biologically active substance enriched with proteins and regenerative mediators, offering therapeutic potential in wound ...