Nasopharyngeal carcinoma (NPC) originates from the epithelial cells of the nasopharynx. A high incidence is found in China and the Southeast Asia including Thailand. Wnt signaling has been shown to be implicated in the development and progression of many types of cancer. Here we aimed to investigate WNT8B protein expression in NPC patients using tissue microarray analysis and to evaluate its correlation with patient survival and clinical parameters. We found that WNT8B protein expression was significantly correlated with the survival of NPC patients. Thus, it is possible that WNT8B is involved in the progression and poor prognosis of NPC.
Ngernsombat C, Prattapong P, Larbcharoensub N, Khotthong K, Janvilisri T. WNT8B as an Independent Prognostic Marker for Nasopharyngeal Carcinoma. Current Oncology. 2021; 28(4):2529-2539. https://doi.org/10.3390/curroncol28040230
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