Anti-cancer Activity of Ethanolic Extract from ‘Bao’ mango (Mangifera indica) Peel and Its Nanoencapsulation Against Triple-Negative Breast Cancer Cell Lines

  This work, ‘Bao’ mango peel extract (MPE) was investigated for its antioxidant and anti-cancer activities. Furthermore, after encapsulation with chitosan-coated poly(lactic-co-glycolic acid) (PLGA/CS) nanoparticles, it showed increasing of anticancer activity by affecting cell viability and inhibiting the cell migration and invasion of MDA-MB-231 breast cancer cells, compared to the free MPE. Therefore, these findings indicated that MPE and CS-PLGA-(MPE) nanoparticles could be promising alternatives to chemicals used for breast cancer treatment.

Reference

Kumkoon T, Chunhavacharatorn P, Manohong P, Nirmal N, Benjakul S, and Katewongsa KP* Anti-cancer Activity of Ethanolic Extract from ‘Bao’ mango (Mangifera indica) Peel and Its Nanoencapsulation Against Triple-Negative Breast Cancer Cell Lines. ChemNanoMat. 2024. e202300530.

DOI: 10.1002/cnma.202300530