New research highlights a powerful way to block aggressive colon and breast cancers by cutting off the energy and fats they need to grow. The
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The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis
Mallotumide A, a natural compound derived from plant roots, has shown high effectiveness in halting the spread and growth of aggressive colon and breast cancer
Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration
This research reveals that Erianin, a natural compound found in orchids, can effectively prevent the formation of new fat cells without being toxic to the
Discovery and biochemical characterization of enzymes completing the 4-hydroxyphenylacetate pathway in Acinetobacter baumannii TH
The 4-hydroxyphenylacetate (4-HPA) degradation pathway enables environmental and pathogenic microbes to assimilate aromatic compounds, yet several steps in Acinetobacter baumannii TH remain unclear. While enzymes
Structure and reaction mechanisms of a two-component indole monooxygenase from Acinetobacter baumannii
This study investigates how two-component indole monooxygenase from Acinetobacter baumannii converts indole into 3-hydroxyindole. The enzyme system consists of two cooperating proteins: reductase supplies reduced
Enhancing plant growth using anaerobic co-digestate of pig manure, food waste, and coffee grounds
This study demonstrates the use of anaerobic co-digestate liquid (AcoDL) derived from pig manure inoculum, food waste, and spent coffee grounds (PMI/FW/SCG) as a sustainable
Association of a CD44s-v5-v6 Null Phenotype with Advanced Stage Cholangiocarcinoma: A Preliminary Study
Cholangiocarcinoma is a very aggressive bile duct cancer with poor survival rates, making it crucial for doctors to better predict patient outcomes. Scientists have long
Kinetic analysis of catalytic activity of G-quadruplex/hemin DNAzyme with flanking adenine nucleotides
This study shows that adding adenine (A) bases to the 3′ end of a G-quadruplex/hemin DNAzyme greatly boosts its enzyme-like activity. The modified DNAzyme became
Biologics, Biosimilars, and Biobetters: Therapeutic Innovations Reshaping Modern Medicine
Biologic medicines are advanced drugs made from living cells. They are effective for treating cancer and other serious diseases, but they are very expensive to
BC Faculty Seminar: December 3, 2025
“Plant-derived cyclopeptide and bibenzyl compound with anti-neoplastic and anti-adipogenesis activities” by Prof. Sarawut Jitrapakdee Department of Biochemistry, Faculty of Science Mahidol University Date: December 3,