This is the first report to identify gene in coconut responsible for curd phenotype. The gene is endosperm specific α-galactosidase. DNA encoding α-galactosidase gene alleles
Category: BC Research
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Development and Validation of an Enzymatic Method to Determine Stevioside Content from Stevia rebaudiana
We established enzymatic method for specific determination of stevioside content. The key enzyme came from recombinant β-glucosidase BT_3567 (rBT_3567) from Bacteroides thetaiotaomicron HB-13 which exhibited
Proteomic analysis reveals distinct protein corona compositions of citrate- and riboflavin- coated SPIONs
This work, we reported the protein corona analysis of citrate- and riboflavin- coated superpartamagnetic iron oxide nanoparticles. Both are widely used as surface coating and
Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach
Cholangiocarcinoma (CCA) has a complex immune microenvironment architecture, thus possessing challenges in its characterization and treatment. This study aimed to repurpose FDA-approved drugs for
In Silico Target Identification of Galangin, as an Herbal Flavonoid against Cholangiocarcinoma
Cholangiocarcinoma (CCA) is a heterogenous group of malignancies in the bile duct which proliferates aggressively. As a result, most patients are diagnosed in advanced
Druggable Allosteric Sites in β-Propeller Lectins
β-Propeller lectins are a group of carbohydrate binding proteins consisting of repetitive protomers arranged in a propeller configuration. These lectins emerged as new targets for
Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecA
LecA is a carbohydrate-binding protein released by an opportunistic bacterium Pseudomonas aeruginosa, as part of a myriad of virulence factors and thus, a prime therapeutic
Targeting undruggable carbohydrate recognition sites through focused fragment library design
Carbohydrate binding proteins are therapeutic targets because of their key role in host-pathogen recognition and cell-to-cell communication. Unfortunately, the hydrophilic nature of the carbohydrate binding
PGE 2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
In collaboration with Dr. Dean Thumkeo and his team, Charoensawan laboratory at Department of Biochemistry, Faculty of Science, has contributed its expertise in single-cell transcriptomic
Potential Role of the Host-Derived Cell-Wall Binding Domain of Endolysin CD16/50L as a Molecular Anchor in Preservation of Uninfected Clostridioides difficile for New Rounds of Phage Infection
Endolysin is a peptidoglycan hydrolase encoded in a phage genome. The enzyme is attractive due to its potential use as antibacterial treatment. ABSTRACT Endolysin is