In vitro analysis of the anticancer activity of Lysinibacillus sphaericus binary toxin in human cancer cell lines

    Bin toxins are potent against mosquito larvae. Recently, their anticancer activities are also shown. Here we showed possible anticancer activity of Bin toxin produced by Lysinibacillus sphaericus. Treatment with a high concentration of Bin inhibits cell proliferation in various human cancer cells This work suggests that Bin toxin may be optimized as a novel potential cancer-therapeutic agent.

Reference:

Chankamngoen W, Janvilisri T, Promdonkoy B, Boonserm P. In vitro analysis of the anticancer activity of Lysinibacillus sphaericus binary toxin in human cancer cell lines. 3 Biotech. 2020 Aug;10(8):365.