New research highlights a powerful way to block aggressive colon and breast cancers by cutting off the energy and fats they need to grow. The
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The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis
Mallotumide A, a natural compound derived from plant roots, has shown high effectiveness in halting the spread and growth of aggressive colon and breast cancer
Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration
This research reveals that Erianin, a natural compound found in orchids, can effectively prevent the formation of new fat cells without being toxic to the
BC Faculty Seminar: December 3, 2025
“Plant-derived cyclopeptide and bibenzyl compound with anti-neoplastic and anti-adipogenesis activities” by Prof. Sarawut Jitrapakdee Department of Biochemistry, Faculty of Science Mahidol University Date: December 3,
Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model
This research emphasizes the potential of photothermal therapy (PTT) as an effective cancer treatment using nanomaterials. By utilizing photosensitizers that
Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells
Cholangiocarcinoma (CCA) is a type of cancer that affects the lining of the bile ducts and is particularly common in East Asia and Thailand. The
MicroRNA expression profiles associated with the metastatic ability of MDA‑MB‑231 breast cancer cells
Breast cancer is an important worldwide public health concern and its incidence increases every year. MicroRNAs (miRs/miRNAs) are small non-coding RNAs that control gene expression
Anti-Xanthine Oxidase 5′-Hydroxyhericenes A-D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol
Hericium erinaceus is an edible mushroom with diverse pharmaceutical applications. Although this mushroom is an attractive source of natural products for cancer treatment, little is
Proteomic analysis of holocarboxylase synthetase deficient-MDA-MB-231 breast cancer cells revealed the biochemical changes associated with cell death, impaired growth signaling, and metabolism
Holocarboxylase synthetase (HLCS) is the enzyme that regulates biotin carboxylase activities, and plays an important role in cancer metabolism. Here, we investigated the global biochemical
BC Faculty Seminar: January 10, 2024
BC Faculty Seminar “Development of smart nano-delivery platforms targeting colorectal cancer for personalized medicine: A showcase of ZY-444 small molecule targeting pyruvate carboxylase.” by Prof. Sarawut