Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence

Varodom Charoensawan

          Dr. Charoensawan and his team have analyzed single-cell transcriptomic profiles of the peripheral blood mononuclear cell samples from two DENV patients, collected daily during acute phase and also at convalescence, and demonstrated different dynamic responses over the course of the infection. On Read More …

Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts

Varodom Charoensawan

  Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts In collaboration with Dr Chalermchai Mitrpant, Charoensawan laboratory at Department of Biochemistry, Faculty of Science, has contributed to the transcriptomic analyses showing that splice Read More …

Capturing tumour heterogeneity in pre- and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing

Varodom Charoensawan

    Capturing tumour heterogeneity in pre- and post-chemotherapy colorectal cancer ascites-derived cells using single-cell RNA-sequencing   Dr. Charoensawan and his colleagues have employed single-cell RNA-sequencing (scRNA-seq) to explore and characterise ascites-derived cells from a colorectal cancer CRC patient. Analysis Read More …