Bin toxins are potent against mosquito larvae. Recently, their anticancer activities are also shown. Here we showed possible anticancer activity of Bin toxin produced by Lysinibacillus sphaericus. Treatment with a high concentration of Bin inhibits cell proliferation in various human cancer cells This work suggests that Bin toxin may be optimized as a novel potential cancer-therapeutic agent.
Chankamngoen W, Janvilisri T, Promdonkoy B, Boonserm P. In vitro analysis of the anticancer activity of Lysinibacillus sphaericus binary toxin in human cancer cell lines. 3 Biotech. 2020 Aug;10(8):365.
|Download the article at
|Assoc. Prof.Tavan Janvilisri