Dr. Charoensawan and his team have analyzed single-cell transcriptomic profiles of the peripheral blood mononuclear cell samples from two DENV patients, collected daily during acute phase and
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Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts
Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of SMN2 in SMA Type I Fibroblasts In collaboration with Dr Chalermchai Mitrpant, Charoensawan laboratory at
BC Special Seminar: April 7, 2022
BC Faculty Seminar “Bacterial CRISPR tools for metabolic engineering applications” by Cholpisit Kiattisewee EBRC SPA-Board Ph.D. Candidate in Molecular Engineering and Sciences, University of Washington, USA
BC Faculty Seminar: March 2, 2022
BC Faculty Seminar “Cholangiocarcinoma and its tumor microenvironment: Role of extracellular matrix” by Assoc. Prof. Tuangporn Suthiphongchai Department of Biochemistry, Faculty of Science, Mahidol University
BC Faculty Seminar: February 9, 2022
BC Faculty Seminar “Vasculogenic mimicry in pancreatic cancer – no blood vessel, no problem” by Assoc. Prof. Thaned Kangsamaksin Department of Biochemistry, Faculty of Science,
The role of the phosphate groups of trinitrophenyl adenosine 5′-triphosphate (TNP-ATP) in allosteric activation of pyruvate carboxylase and the inhibition of acetyl CoA-dependent activation
Pyruvate carboxylase (PC) (EC 6.4.1.1) is a biotin-dependent carboxylase which catalyzes the ATP-dependent carboxylation of pyruvate to form oxaloacetate which is an important precursor
Impaired G2/M cell cycle arrest induces apoptosis in pyruvate carboxylase knockdown MDA-MB-231 cells
The tricarboxylic acid (TCA) cycle functions as both an oxidative hub to oxidize acetyl-CoA and a biosynthetic hub for the synthesis of nucleotides,
Five-(Tetradecyloxy)-2-furoic Acid Alleviates Cholangiocarcinoma Growth by Inhibition of Cell-cycle Progression and Induction of Apoptosis
Metabolic reprograming in cancers is one of cancer hallmarks that allow cancer cell to expand and metastasize to other organs. In collaboration with Assoc Prof
Pyruvate carboxylase supports basal ATP-linked respiration in human pluripotent stem cell-derived brown adipocytes
Brown adipose tissue or BAT is the adipocytes that have a specific physiology in maintaining body temperature via thermogenesis. BAT activity is mainly
Differential growth inhibition, cell cycle arrest and apoptosis of MCF-7 and MDA-MB-231 cells to holocarboxylase synthetase suppression
Metabolic reprograming in cancers is one of cancer hallmarks that allow cancer cell to expand and metastasize to other organs. Professor Sarawut