![Anti-Xanthine Oxidase 5′-Hydroxyhericenes A-D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol](https://biochemistry.sc.mahidol.ac.th/wp-content/uploads/2018/02/SJ-1.jpg)
Hericium erinaceus is an edible mushroom with diverse pharmaceutical applications. Although this mushroom is an attractive source of natural products for cancer treatment, little is
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Proteomic analysis of holocarboxylase synthetase deficient-MDA-MB-231 breast cancer cells revealed the biochemical changes associated with cell death, impaired growth signaling, and metabolism
Holocarboxylase synthetase (HLCS) is the enzyme that regulates biotin carboxylase activities, and plays an important role in cancer metabolism. Here, we investigated the global biochemical
BC Special Seminar: January 15, 2024
BC Special Seminar “Science Careers in Pharma Beyond the Bench” by Chatarin (Chad) Wangsanuwat, Ph.D. University of California, Santa Barbara Current position: Senior Scientist, Moderna
BC Special Seminar: January 24, 2024
BC Special Seminar “Science Careers in Pharma Beyond the Bench” by Dr. Oleg Lavrukhin Regional Field Medical Lead Sanofi US Time: 1:00-2:00 pm Venue:
BC Faculty Seminar: January 10, 2024
BC Faculty Seminar “Development of smart nano-delivery platforms targeting colorectal cancer for personalized medicine: A showcase of ZY-444 small molecule targeting pyruvate carboxylase.” by Prof. Sarawut
Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells
Cholangiocarcinoma (CCA), a bile duct cancer, is an aggressive cancer with poor prognosis. It is typically recognized by its dense extracellular matrix nature which associated
Proteomic Analysis and Molecular Dynamics Simulation of Riboflavin-Coated Superparamagnetic Iron Oxide Nanoparticles Reveal Human Serum-Derived Protein Coronas: Implications as Magnetic Resonance Imaging Contrast Agents
This work, protein coronas of bare, citrate-coated, and Rf-coated SPIONs formed with human serum (HS) were studied by proteomic analysis to identify and quantify the
Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase
Methylenetetrahydrofolate reductase (MTHFR) is a key metabolic enzyme in colonization and virulence of Neisseria meningitidis, a causative agent of meningococcal diseases. In this study,
Mangiferin is a new potential antimalarial and anticancer drug for targeting serine hydroxymethyltransferase
Serine hydroxymethyltransferase (SHMT) is a key enzyme in the deoxythymidylate synthesis cycle, essential for pathogen proliferations, including malaria parasite. Therefore, SHMT is an attractive
Reaction mechanism and kinetics of the two-component flavoprotein dimethyl sulfone monooxygenase system: Using hydrogen peroxide for monooxygenation and substrate cleavage
Dimethyl sulfone monooxygenase catalyzes the oxidative cleavage of dimethyl sulfone (DMSO2) to produce methanesulfinate and formaldehyde. It is a two-component monooxygenase composed of a