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Category: BC Research

for Research Highlights only

Development and in vitro evaluation of ursolic acid-loaded poly(lactic-co-glycolic acid) nanoparticles in cholangiocarcinoma

Development and in vitro evaluation of ursolic acid-loaded poly(lactic-co-glycolic acid) nanoparticles in cholangiocarcinoma

Cholangiocarcinoma (CCA) is a type of cancer that affects the bile ducts and is a major health issue in northeastern Thailand and nearby areas. It

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Mechanisms and applications of bacterial luciferase and its auxiliary enzymes

Mechanisms and applications of bacterial luciferase and its auxiliary enzymes

        Bacterial luciferase (LuxAB) catalyzes the conversion of reduced flavin mononucleotide (FMNH2), oxygen, and a long-chain aldehyde to oxidized FMN, the corresponding

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KHDRBS3 facilitates self-renewal and temozolomide resistance of glioblastoma cell lines

KHDRBS3 facilitates self-renewal and temozolomide resistance of glioblastoma cell lines

Glioblastoma is a highly aggressive and fatal tumor characterized by the presence of glioblastoma stem cells (GSCs), which contribute significantly to tumor recurrence and resistance

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Combinatorial effects of cannabinoid receptor 1 and 2 agonists on characteristics and proteomic alteration in MDA-MB-231 breast cancer cells

Combinatorial effects of cannabinoid receptor 1 and 2 agonists on characteristics and proteomic alteration in MDA-MB-231 breast cancer cells

The activation of cannabinoid receptor (CB) has been shown to negatively affect breast cancer cell survival. Our previous study also reported that breast cancer cells

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Identification of transcriptional regulators of immune evasion across cancers: an alternative immunotherapeutic strategy for cholangiocarcinoma

Identification of transcriptional regulators of immune evasion across cancers: an alternative immunotherapeutic strategy for cholangiocarcinoma

Current immunotherapies are ineffectively designed toward single-target inhibition in a complex multifactored process. Moreover, available therapeutics are incapable of meeting the needs of the expanding

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Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model

Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model

          This research emphasizes the potential of photothermal therapy (PTT) as an effective cancer treatment using nanomaterials. By utilizing photosensitizers that

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Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells

Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells

Cholangiocarcinoma (CCA) is a type of cancer that affects the lining of the bile ducts and is particularly common in East Asia and Thailand. The

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SRPK Inhibitors Reduce the Phosphorylation and Translocation of SR Protein Splicing Factors, thereby Correcting BIN1, MCL-1 and BCL2 Splicing Errors and Enabling Apoptosis of Cholangiocarcinoma Cells

SRPK Inhibitors Reduce the Phosphorylation and Translocation of SR Protein Splicing Factors, thereby Correcting BIN1, MCL-1 and BCL2 Splicing Errors and Enabling Apoptosis of Cholangiocarcinoma Cells

  Cholangiocarcinoma (CCA), a common bile duct cancer in Thailand, has poor survival rates due to limited diagnostic and treatment options. mRNA splicing errors, driven

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Identification and preclinical evaluation of MMV676558 as a promising therapeutic candidate against Clostridioides difficile

Identification and preclinical evaluation of MMV676558 as a promising therapeutic candidate against Clostridioides difficile

          Clostridioides difficile is a bacterium that causes severe diarrhea, especially after antibiotic use. Current treatments, like fidaxomicin and vancomycin, work for initial infections, but

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Quantum dots as a fluorescent labeling tool for live-cell imaging of Leptospira.

Quantum dots as a fluorescent labeling tool for live-cell imaging of Leptospira.

In this study, cadmium telluride quantum dots (CdTe QDs) was synthesized and modified surface with concanavalin A (ConA), a carbohydrate-binding lectin and known biological probe

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© 2024 Department of Biochemistry, Faculty of Science, Mahidol University
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