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Category: BC Research

for Research Highlights only

Identification and preclinical evaluation of MMV676558 as a promising therapeutic candidate against Clostridioides difficile

Identification and preclinical evaluation of MMV676558 as a promising therapeutic candidate against Clostridioides difficile

          Clostridioides difficile is a bacterium that causes severe diarrhea, especially after antibiotic use. Current treatments, like fidaxomicin and vancomycin, work for initial infections, but

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Quantum dots as a fluorescent labeling tool for live-cell imaging of Leptospira.

Quantum dots as a fluorescent labeling tool for live-cell imaging of Leptospira.

In this study, cadmium telluride quantum dots (CdTe QDs) was synthesized and modified surface with concanavalin A (ConA), a carbohydrate-binding lectin and known biological probe

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Antioxidant and antimicrobial activities of mango peel and radish peel-a comparative investigation

Antioxidant and antimicrobial activities of mango peel and radish peel-a comparative investigation

  The study explored the antioxidant and antimicrobial properties of ethanolic extracts from Bao Mango and Thai daikon radish peels. It found that the extraction

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Anti-cancer Activity of Ethanolic Extract from ‘Bao’ mango (Mangifera indica) Peel and Its Nanoencapsulation Against Triple-Negative Breast Cancer Cell Lines

Anti-cancer Activity of Ethanolic Extract from ‘Bao’ mango (Mangifera indica) Peel and Its Nanoencapsulation Against Triple-Negative Breast Cancer Cell Lines

  This work, ‘Bao’ mango peel extract (MPE) was investigated for its antioxidant and anti-cancer activities. Furthermore, after encapsulation with chitosan-coated poly(lactic-co-glycolic acid) (PLGA/CS) nanoparticles,

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The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile: evolution and drug resistance perspective

The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile: evolution and drug resistance perspective

        Secondary active transporters move substances across cell membranes in both eukaryotic and prokaryotic organisms, using different electrochemical gradients and contributing to

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Development of Carbon Dots Synthesized from Green Tea and Alpha-Hydroxyl Acids with Enhanced Antioxidant Activity, Photostability and UV Protection Properties

Development of Carbon Dots Synthesized from Green Tea and Alpha-Hydroxyl Acids with Enhanced Antioxidant Activity, Photostability and UV Protection Properties

        The exhaustion of the ozone layer in the atmosphere has increased UV radiation penetrating the earth’s surface, leading to severe skin health risks, such as

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Preparation of Decellularized Tissue as Dual Cell Carrier Systems: A Step Towards Facilitating Re-epithelization and Cell Encapsulation for Tracheal Reconstruction

Preparation of Decellularized Tissue as Dual Cell Carrier Systems: A Step Towards Facilitating Re-epithelization and Cell Encapsulation for Tracheal Reconstruction

        Tissue-based treatments, involving the cultivation of patient cells on a network of extracellular matrix (ECM) from donor tissue, hold promise for restoring tracheal structure and

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BRCA1 deficiency enhances the aggressiveness of breast cancer cells expressing HPV16 oncoproteins

BRCA1 deficiency enhances the aggressiveness of breast cancer cells expressing HPV16 oncoproteins

        The precise etiology of breast cancer is not completely understood, although women with inherited BRCA1 gene mutations or decreased BRCA1 expression

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Chitosan-Coated Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Ursolic Acid for Breast Cancer Therapy

Chitosan-Coated Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Ursolic Acid for Breast Cancer Therapy

  This work, we used chitosan-coated poly(lactic-co-glycolic acid) (PLGA/CS) nanoparticles to encapsulate ursolic acid (UA). UA is a pentacyclic triterpenoid found in various fruits and

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Identification of a microbial sub-community from the feral chicken gut that reduces Salmonella colonization and improves gut health in a gnotobiotic chicken model

Identification of a microbial sub-community from the feral chicken gut that reduces Salmonella colonization and improves gut health in a gnotobiotic chicken model

          In a quest to understand the battlefield of gut microbiomes, we explored 1,300 bacterial strains from chicken guts, pinpointing 30 that battle Salmonella. They

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© 2024 Department of Biochemistry, Faculty of Science, Mahidol University
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