Dimethyl sulfone monooxygenase catalyzes the oxidative cleavage of dimethyl sulfone (DMSO2) to produce methanesulfinate and formaldehyde. It is a two-component monooxygenase composed of a
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BC Faculty Seminar: August 9, 2023
BC Faculty Seminar “Dehydrogenases: Mechanism insight and its versatile applications” by Assoc. Prof. Ruchanok Tinikul Department of Biochemistry, Faculty of Science, Mahidol University Date: Wednesday,
Congratulations to Asst. Prof. Dr. Ruchanok Tinikul
Congratulations to Asst. Prof. Dr. Ruchanok Tinikul on being promoted to “Associate Professor”
Detection of cellular metabolites by redox enzymatic cascades
The measurement of cellular metabolites is crucial for medical applications as specific biomarkers can serve as disease indicators, while the detection of microbial metabolites
QM/MM molecular modeling reveals mechanism insights into flavin peroxide formation in bacterial luciferase
Bacterial luciferase (Lux) catalyzes light-emitting reactions, and the enzyme has long been used as a sensitive detection tool in biomedical, food, and environmental applications.
Luciferin synthesis and pesticide detection by luminescence enzymatic cascades
This research reported a novel, efficient, and green method to use enzymatic cascades, including esterase for pesticide transformation, flavin monooxygenase (HadA) for dehalogenation, flavin
Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii
Aldolase catalyzes reversible C-C bond condensation and joining. Its reaction is useful in biochemical synthesis, participating in extending the carbon chain length of a
Protonation status and control mechanism of flavin–oxygen intermediates in the reaction of bacterial luciferase
Protonation status and control mechanism of flavin–oxygen intermediates in the reaction of bacterial luciferase Bacterial luciferase catalyzes bioluminescent reaction that has long been
Addition of formate dehydrogenase increases the production of renewable alkane from an engineered metabolic pathway
Addition of formate dehydrogenase increases the production of renewable alkane from an engineered metabolic pathway An engineered metabolic pathway to convert fatty acids
A Minimized chemoenzymatic cascade for bacterial luciferase in bioreporter applications
A Minimized chemoenzymatic cascade for bacterial luciferase in bioreporter applications Bacterial luciferase (Lux) generates bioluminescent reaction by using long chain aldehyde, reduced FMN
