Overexpression of Holocarboxylase Synthetase Predicts Lymph Node Metastasis and Unfavorable Prognosis in Breast Cancer

Sarawut Jitrapakdee

Overexpression of Holocarboxylase Synthetase Predicts Lymph Node Metastasis and Unfavorable Prognosis in Breast Cancer Witchuda Sukjoi1, Siraprapa Siritutsoontorn1, Pakkanan Chansongkrow1, Suppakit Waiwitlikhit1,2, Steven W. Polyak3, Malee Warnnissorn4, Varodom Charoensawan1,5,6,Chanitra Thuwajit7, Sarawut Jitrapakdee1* 1Department of Biochemistry, Faculty of Science, Mahidol University, Read More …

Overexpression of Pyruvate Carboxylase Is Correlated With Colorectal Cancer Progression and Supports Growth of Invasive Colon Cancer HT-29 Cell Line

Sarawut Jitrapakdee

Overexpression of Pyruvate Carboxylase Is Correlated With Colorectal Cancer Progression and Supports Growth of Invasive Colon Cancer HT-29 Cell Line   Jarunya Ngamkham1, Chanitra Thuwajit2, Peti Thuwajit2, Peerapat Khamwachirapitha3, Kornkamon Lertsuwan3, Varodom Charoensawan3,4,5 and Sarawut Jitrapakdee3   1Graduate Program in Read More …

Characterization of intra- and inter-species hybrid tetramers of pyruvate carboxylase: Biotin and the BCCP domain play a crucial role in determination of the kinetics and thermodynamics of catalysis

Sarawut Jitrapakdee

Characterization of intra- and inter-species hybrid tetramers of pyruvate carboxylase: Biotin and the BCCP domain play a crucial role in determination of the kinetics and thermodynamics of catalysis Khanti Rattanapornsompong, Sarawut Jitrapakdee1 and Paul V. Attwood2 1Department of Biochemistry, Faculty Read More …

Probiotic Activity of Enterococcus faecium and Lactococcus lactis Isolated from Thai Fermented Sausages and Their Protective Effect Against Clostridium difficile

Tavan Janvilisri

     Here, we isolated good bacteria from Nham, Thai-fermented sausages and tested their probiotic potentials against Clostridium difficile pathogen. We found that both Enterococcus faecium and Lactococcus lactis could attach to the cells and survive well after ingestion through our simulated Read More …

Lectin affinity chromatography and quantitative proteomic analysis reveal that galectin-3 is associated with metastasis in nasopharyngeal carcinoma

Tavan Janvilisri

     Nasopharyngeal carcinoma (NPC) originates from the epithelial cells of the nasopharynx. A high incidence is found in China and the Southeast Asia including Thailand. Here we searched for potential glycoprotein biomarkers responsible for metastasis using proteomics. We showed, for the Read More …