Bacterial luciferase (Lux) catalyzes light-emitting reactions, and the enzyme has long been used as a sensitive detection tool in biomedical, food, and environmental applications.
Category: BC Research
for Research Highlights only
Luciferin synthesis and pesticide detection by luminescence enzymatic cascades
This research reported a novel, efficient, and green method to use enzymatic cascades, including esterase for pesticide transformation, flavin monooxygenase (HadA) for dehalogenation, flavin
Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii
Aldolase catalyzes reversible C-C bond condensation and joining. Its reaction is useful in biochemical synthesis, participating in extending the carbon chain length of a
Enhanced Functional Properties of Three DNA Origami Nanostructures as Doxorubicin Carriers to Breast Cancer Cells
Our group demonstrated that DNA origami nanostructures with different structural designs exhibited different drug delivery functionalities. We investigated three nanostructures: Disc, Donut, and Sphere,
Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
The endocannabinoid system has been postulated to help restrict cancer progression and maintain osteoblastic function during bone metastasis. Herein, the effects of cannabinoid receptor (CB)
Riboflavin-citrate conjugate multicore SPIONs with enhanced magnetic responses and cellular uptake in breast cancer cells
This work, we developed a novel riboflavin (Rf) functionalized superparamagnetic iron oxide nanoparticles (SPIONs) that has been beneficial in the advancement of contrast agents and
Hepcidin induces intestinal calcium uptake while suppressing iron uptake in Caco-2 cells
Abnormal calcium absorption and iron overload from iron hyperabsorption can contribute to osteoporosis as found in several diseases, including hemochromatosis and thalassemia. Previous studies in
Analysis of laminins’ cognate receptors reveals the upregulation of ITGB4 in CCA tissues
Cholangiocarcinoma (CCA) is a rare but highly lethal cancer arising from biliary tract. Its incidence is highest in Northeast, Thailand (about 100
Molecularly Guided Drug Repurposing for Cholangiocarcinoma: An Integrative Bioinformatic Approach
Cholangiocarcinoma (CCA) has a complex immune microenvironment architecture, thus possessing challenges in its characterization and treatment. This study aimed to repurpose FDA-approved
Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence
Dr. Charoensawan and his team have analyzed single-cell transcriptomic profiles of the peripheral blood mononuclear cell samples from two DENV patients, collected daily during acute phase and